14365-44-7
14365-44-7
Chemical Structure
5'-Amino-5'-deoxyadenosine
Synonym(s): NH2dAdo; Nsc 238990
- CAS 番号: 14365-44-7
- Formula:C10H14N6O3
- Molecular Weight:266.26
IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol
InChIKey: GVSGUDGNTHCZHI-KQYNXXCUSA-N
SMILES: O[C@@H]1[C@@H](CN)O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@@H]1O
Biological Activity: 5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog and a 5'-deoxyadenosine derivative. 5'-Amino-5'-deoxyadenosine inhibits vaccinia virus (CV) proliferation in cultured cells. 5'-Amino-5'-deoxyadenosine can be used in research on vaccinia virus infection[1][2].
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5'-Amino-5'-deoxyadenosine | 96.40% | 5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog and a 5'-deoxyadenosine derivative. 5'-Amino-5'-deoxyadenosine inhibits vaccinia virus (CV) proliferation in cultured cells. 5'-Amino-5'-deoxyadenosine can be used in research on vaccinia virus infection. | ||||||||||||||||||||
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References
- [1]. Grytzmann B, et al. Derivatives of 3'- and 5'-deoxyadenosine: their inhibitory activity against DNA viruses. Chemotherapy. 1980;26(5):316-22. [Content Brief]
- [2]. Robak T, et al. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Current pharmaceutical design. 2012;18(23):3373-88. [Content Brief]
