144450-13-5
144450-13-5
Chemical Structure
Tyr-W-MIF-1
- CAS No.: 144450-13-5
- Formula:C27H32N6O5
- Molecular Weight:520.58
InChIKey: HWGSOAJXZHSMGE-PMVMPFDFSA-N
SMILES: O=C(NCC(N)=O)[C@@H](NC([C@H](CCC1)N1C([C@@H](N)CC(C=C2)=CC=C2O)=O)=O)CC3=CNC4=CC=CC=C34
Biological Activity: Tyr-W-MIF-1 is an opioid tetrapeptide with opiate and antiopiate activity. Tyr-W-MIF-1 can induce analgesia[1][2][5].
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Tyr-W-MIF-1 | Tyr-W-MIF-1 is an opioid tetrapeptide with opiate and antiopiate activity. Tyr-W-MIF-1 can induce analgesia. | |||||||||||||||||||||
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References
- [1]. Yang YR, et L. Opioid and antiopioid actions of Tyr-MIF-1, Tyr-W-MIF-1 and hemorphin-4 on rat locus coeruleus neurons: intracellular recording in vitro. Chin J Physiol. 1997 Sep 30;40(3):131-5. [Content Brief]
- [2]. Gergen KA, et al. Expression of the FOS proto-oncogene protein in brain after ICV administration of Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2). Peptides. 1994;15(8):1505-11. [Content Brief]
- [5]. Erchegyi J, et al. Isolation of a novel tetrapeptide with opiate and antiopiate activity from human brain cortex: Tyr-Pro-Trp-Gly-NH2 (Tyr-W-MIF-1). Peptides. 1992 Jul-Aug;13(4):623-31. [Content Brief]
