1449756-87-9
Chemical Structure
HCV-IN-7 hydrochloride
- CAS No.: 1449756-87-9
- Formula:C40H50Cl2N8O6S
- Molecular Weight:841.85
IUPAC Name: dimethyl ((2S,2'S)-((2S,2'S)-(naphtho[1,2-b]thiophene-2,7-diylbis(1H-imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-1,2-diyl))dicarbamate dihydrochloride
InChIKey: HVGIKJUXPYMGSR-RADXRPBUSA-N
SMILES: [H]Cl.[H]Cl.O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)[C@@H]1C(N2)=NC=C2C3=CC(C=C4)=C(S3)C5=C4C=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CCC7)N6)C=C5
Biological Activity: HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor with IC50s of 3-47 pM. HCV-IN-7 hydrochloride shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake. HCV-IN-7 hydrochloride has anti-viral activity[1].
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HCV-IN-7 hydrochloride | HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor with IC50s of 3-47 pM. HCV-IN-7 hydrochloride shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake. HCV-IN-7 hydrochloride has anti-viral activity. | |||||||||||||||||||||
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