150010-68-7
150010-68-7
Chemical Structure
LY 215490
- CAS No.: 150010-68-7
- Formula:C13H21N5O2
- Molecular Weight:279.34
IUPAC Name: (3R,4aS,6S,8aS)-6-(2-(1H-tetrazol-5-yl)ethyl)decahydroisoquinoline-3-carboxylic acid
InChIKey: ZXFRFPSZAKNPQQ-ZRUFSTJUSA-N
SMILES: OC([C@@H](C1)NC[C@](CC2)([H])[C@@]1([H])C[C@@H]2CCC3=NN=NN3)=O
Biological Activity: LY 215490 is a selective, competitive AMPA receptor antagonist against AMPA, CGSl9755 and kainate with IC50 values of 4.8, 26.4 and 247 μM, respectively. LY 215490 shows neuroprotective effects in focal ischaemia[1].
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LY 215490 | LY 215490 is a selective, competitive AMPA receptor antagonist against AMPA, CGSl9755 and kainate with IC50 values of 4.8, 26.4 and 247 μM, respectively. LY 215490 shows neuroprotective effects in focal ischaemia. | |||||||||||||||||||||
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