LY 215490
LY 215490 is a selective, competitive AMPA receptor antagonist against AMPA, CGSl9755 and kainate with IC50 values of 4.8, 26.4 and 247 μM, respectively. LY 215490 shows neuroprotective effects in focal ischaemia.
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- CAS. Nr.: 150010-68-7
- Formel: C13H21N5O2
- Molecular Weight:279.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 150010-68-7
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Molecular Weight 279.34
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Formel C13H21N5O2
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SMILES
OC([C@@H](C1)NC[C@](CC2)([H])[C@@]1([H])C[C@@H]2CCC3=NN=NN3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Gill R, et al. The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia. Neuropharmacology. 1994 Dec;33(12):1529-36. [Content Brief]
[2]. Ornstein PL, et al. (3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist. J Med Chem. 1993 Jul 9;36(14):2046-8. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
LY 215490 Related Classifications
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