LY 215490
LY 215490 is a selective, competitive AMPA receptor antagonist against AMPA, CGSl9755 and kainate with IC50 values of 4.8, 26.4 and 247 μM, respectively. LY 215490 shows neuroprotective effects in focal ischaemia.
For research use only. We do not sell to patients.
- CAS No.: 150010-68-7
- Formula: C13H21N5O2
- Molecular Weight:279.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Description
Chemical Information
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CAS No. 150010-68-7
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Molecular Weight 279.34
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Formula C13H21N5O2
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SMILES
OC([C@@H](C1)NC[C@](CC2)([H])[C@@]1([H])C[C@@H]2CCC3=NN=NN3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gill R, et al. The neuroprotective effects of the decahydroisoquinoline, LY 215490; a novel AMPA antagonist in focal ischaemia. Neuropharmacology. 1994 Dec;33(12):1529-36. [Content Brief]
[2]. Ornstein PL, et al. (3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist. J Med Chem. 1993 Jul 9;36(14):2046-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LY 215490 Related Classifications
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