155730-92-0
155730-92-0
Chemical Structure
S-2E
- CAS No.: 155730-92-0
- Formula:C22H25NO4
- Molecular Weight:367.44
IUPAC Name: (S)-4-((1-(4-(tert-butyl)phenyl)-5-oxopyrrolidin-3-yl)methoxy)benzoic acid
InChIKey: YZADMDZNVOBYGR-HNNXBMFYSA-N
SMILES: O=C1N(C2=CC=C(C=C2)C(C)(C)C)C[C@H](C1)COC3=CC=C(C=C3)C(O)=O
Biological Activity: S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research[1][2].
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S-2E | S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research. | |||||||||||||||||||||
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References
- [1]. Koichi Ohmori, et al. Anti-hyperlipidemic action of a newly synthesized benzoic acid derivative, S-2E. Eur J Pharmacol. 2003 Jun 13;471(1):69-76. [Content Brief]
- [2]. K Ohmori, et al. Effects of a novel antihyperlipidemic agent, S-2E, on the blood lipid abnormalities in homozygous WHHL rabbits. Metabolism. 2004 May;53(5):680-5. [Content Brief]
Keywords
