1572414-83-5
1572414-83-5
Chemical Structure
ML-323
- CAS No.: 1572414-83-5
- Formula:C23H24N6
- Molecular Weight:384.48
IUPAC Name: N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine
InChIKey: VUIRVWPJNKZOSS-UHFFFAOYSA-N
SMILES: CC1=CN=C(C2=C(C(C)C)C=CC=C2)N=C1NCC3=CC=C(N4N=NC=C4)C=C3
Biological Activity: ML-323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay. The measured inhibition constants of ML-323 for the free enzyme (Ki) is 68 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ML-323 | 99.51% | ML-323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay. The measured inhibition constants of ML-323 for the free enzyme (Ki) is 68 nM. | ||||||||||||||||||||
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