158747-02-5
158747-02-5
Chemical Structure
Frovatriptan
Synonym(s): (R)-Frovatriptan; SB 209509; VML 251
- CAS No.: 158747-02-5
- Formula:C14H17N3O
- Molecular Weight:243.30
IUPAC Name: (R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide
InChIKey: XPSQPHWEGNHMSK-SECBINFHSA-N
SMILES: O=C(C1=CC2=C(NC3=C2C[C@H](NC)CC3)C=C1)N
Biological Activity: Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1].
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Frovatriptan | Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura. | |||||||||||||||||||||
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Frovatriptan-d3 hydrochloride | Frovatriptan-d3 (hydrochloride) is the deuterium labeled Frovatriptan. Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura. | |||||||||||||||||||||
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References
