159912-53-5
159912-53-5
Chemical Structure
Sabcomeline
Synonym(s): SB-202026; Memric
- CAS No.: 159912-53-5
- Formula:C10H15N3O
- Molecular Weight:193.25
IUPAC Name: (R,Z)-N-methoxyquinuclidine-3-carbimidoyl cyanide
InChIKey: IQWCBYSUUOFOMF-QTLFRQQHSA-N
SMILES: CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N
Biological Activity: Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].
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Sabcomeline | Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research. | |||||||||||||||||||||
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References
- [1]. Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. [Content Brief]
- [2]. Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282. [Content Brief]
