1604811-14-4
Chemical Structure
bio-THZ1
- CAS No.: 1604811-14-4
- Formula:C52H65ClN12O8S
- Molecular Weight:1053.67
IUPAC Name: N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((E)-5-methyl-10,24-dioxo-28-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-14,17,20-trioxa-5,9,11,23-tetraazaoctacos-2-enamido)benzamide
InChIKey: ARPCJVVFIKPHFA-SFDVBDGFSA-N
SMILES: O=C(NCCOCCOCCOCCNC(NCCCN(C)C/C=C/C(NC1=CC=C(C(NC2=CC=CC(NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)=C2)=O)C=C1)=O)=O)CCCC[C@@H]6SC[C@]([C@]6([H])N7)([H])NC7=O
Biological Activity: bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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bio-THZ1 | 98.06% | bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. | ||||||||||||||||||||
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Keywords
