1616473-67-6
1616473-67-6
Chemical Structure
Antitumor agent-209
- CAS No.: 1616473-67-6
- Formula:C22H26FN3O
- Molecular Weight:367.46
InChIKey: IPIAOBLIKHDYCE-UHFFFAOYSA-N
SMILES: FC(C=C1)=CC=C1COC2=CC=C3C(N=CC=C3NCCN(CC)CC)=C2
Biological Activity: Antitumor agent-209 (Compound 10g), a quinolone derivative, is an antitumor agent. Antitumor agent-209 can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 0.37, 0.58, 0.81, 0.79, 0.89, 0.78 and 0.89 μM[1].
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Antitumor agent-209 | Antitumor agent-209 (Compound 10g), a quinolone derivative, is an antitumor agent. Antitumor agent-209 can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 0.37, 0.58, 0.81, 0.79, 0.89, 0.78 and 0.89 μM. | |||||||||||||||||||||
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