1619244-34-6
Chemical Structure
Verlamelin A
- CAS No.: 1619244-34-6
- Formula:C45H71N7O11
- Molecular Weight:886.09
InChIKey: SORSHHMYDAJYHQ-LISZAPCHSA-N
SMILES: O=C1[C@@]2([H])N(C([C@H](NC([C@@](NC(CCC[C@@H](OC([C@@H](NC([C@H](NC([C@@H](N1)CCC(N)=O)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCCCCCCC)=O)([H])[C@H](O)C)=O)C)=O)CCC2
Biological Activity: Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC50 = 16.7 μM). Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Verlamelin A | Verlamelin A is a macrocyclic depsipeptide with antifungal and antiviral activity. Verlamelin A shows antifungal activity toward Aspergillus versicolor and Curvularia australiensis and also has antiviral activity toward HSV-1 (IC50 = 16.7 μM). Verlamelin A is isolated from the entomopathogenic fungus Lecanicillium sp. Verlamelin A is useful for antifungal and antiviral research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Ishidoh K, et al. Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp. J Antibiot (Tokyo). 2014 Jun;67(6):459-63. [Content Brief]
- [2]. Sun X, et al. Total Synthesis of Verlamelin A and (5R)-Verlamelin A with Antifungal Activity. J Org Chem. 2025 Sep 5;90(35):12425-12434. [Content Brief]
- [3]. Liang X, et al. Antifungal and Antiviral Cyclic Peptides from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020. J Agric Food Chem. 2017 Jun 28;65(25):5114-5121. [Content Brief]
Keywords
