169564-26-5
Chemical Structure
7-Descarbamoyl-17-amino geldanamycin
- CAS No.: 169564-26-5
- Formula:C27H38N2O7
- Molecular Weight:502.60
IUPAC Name: (4E,6E,10E)-19-amino-9,13-dihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaene-3,20,22-trione
InChIKey: FQHAJOLMHIBHDX-BHZPMCJBSA-N
SMILES: C[C@H]1C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](O)[C@@H](OC)/C=C/C=C(C)/C(NC2=CC(C(N)=C(C2=O)C1)=O)=O
Biological Activity: 7-Descarbamoyl-17-amino geldanamycin is a Geldanamycin (HY-15230) derivative. 7-Descarbamoyl-17-amino geldanamycin exerts very low activity in depleting p185erbB-2 protein in human breast cancer cells in vitro[1].
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7-Descarbamoyl-17-amino geldanamycin | 7-Descarbamoyl-17-amino geldanamycin is a Geldanamycin (HY-15230) derivative. 7-Descarbamoyl-17-amino geldanamycin exerts very low activity in depleting p185erbB-2 protein in human breast cancer cells in vitro. | |||||||||||||||||||||
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Keywords
