172286-77-0

Homocarbonyltopsentin Chemical Structure
172286-77-0

Chemical Structure

Homocarbonyltopsentin

Synonym(s): PK4C9

  • CAS No.: 172286-77-0
  • Formula:C21H14N4O3
  • Molecular Weight:370.36

IUPAC Name: (5-(1H-indole-3-carbonyl)-1H-imidazol-2-yl)(6-hydroxy-1H-indol-3-yl)methanone

InChIKey: DRCVQVIMGSWRLN-UHFFFAOYSA-N

SMILES: O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5

Biological Activity: Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM[1].

Cat. No. Product Name Purity Description Pricing
HY-117389 		Homocarbonyltopsentin 99.82% Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC50 value of 16 μM.
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