1802848-94-7
1802848-94-7
Chemical Structure
ABBV-318
- CAS No.: 1802848-94-7
- Formula:C20H15F4N3O2
- Molecular Weight:405.35
IUPAC Name: (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone
InChIKey: FWLFRXVPNVBXGR-CQSZACIVSA-N
SMILES: O=C(N1C[C@H](F)CC1)C2=NC3=CC=C(OC4=NC=C(C(F)(F)F)C=C4)C=C3C=C2
Biological Activity: ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain[1].
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ABBV-318 | 98.72% | ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain. | ||||||||||||||||||||
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References
Keywords
