1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. ABBV-318

ABBV-318 

Cat. No.: HY-146069
Handling Instructions

ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain.

For research use only. We do not sell to patients.

ABBV-318 Chemical Structure

ABBV-318 Chemical Structure

CAS No. : 1802848-94-7

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Description

ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain[1].

IC50 & Target[1]

hNav1.7

2.8 μM (IC50)

hNav1.8

3.3 μM (IC50)

Molecular Weight

405.35

Formula

C20H15F4N3O2

CAS No.
SMILES

O=C(N1C[[email protected]](F)CC1)C2=NC3=CC=C(OC4=NC=C(C(F)(F)F)C=C4)C=C3C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ABBV-318
Cat. No.:
HY-146069
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