185843-61-2
Chemical Structure
OGT-719
- CAS No.: 185843-61-2
- Formula:C10H13FN2O7
- Molecular Weight:292.22
IUPAC Name: 5-fluoro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: YHWGRVDTEORPPJ-WENHOLORSA-N
SMILES: O=C1NC(C(F)=CN1[C@H]2[C@@H]([C@H]([C@H]([C@@H](CO)O2)O)O)O)=O
Biological Activity: OGT-719 is a potent, orally active nucleoside analogue that targets the asialoglycoprotein receptor (ASGP-R). OGT-719 inhibits growth of metastatic colorectal tumors in the liver of nude mice. OGT-719 can be used for primary hepatocellular carcinoma and colorectal liver metastases research[1].
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OGT-719 | OGT-719 is a potent, orally active nucleoside analogue that targets the asialoglycoprotein receptor (ASGP-R). OGT-719 inhibits growth of metastatic colorectal tumors in the liver of nude mice. OGT-719 can be used for primary hepatocellular carcinoma and colorectal liver metastases research. | |||||||||||||||||||||
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Keywords
