188818-21-5
188818-21-5
Chemical Structure
EEKLIVVAF
- CAS No.: 188818-21-5
- Formula:C50H82N10O14
- Molecular Weight:1047.24
IUPAC Name: (4aS,9R,10S,10aS)-5,6,10-trihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-9,4a-(epoxymethano)phenanthren-12-one
InChIKey: UZMYABIMZYRHCM-IVWXROFHSA-N
SMILES: OC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CCC(O)=O)NC([C@@H](N)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: EEKLIVVAF is a pepitide, can be recognized on HLA-B44 by the anti-melanoma cytolytic T-cell (CTL) clone LB33- CTL-159/5[1][2].
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EEKLIVVAF | EEKLIVVAF is a pepitide, can be recognized on HLA-B44 by the anti-melanoma cytolytic T-cell (CTL) clone LB33- CTL-159/5. | |||||||||||||||||||||
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References
- [1]. Herman J, et al. Differences in the recognition by CTL of peptides presented by the HLA-B*4402 and the HLA-B*4403 molecules which differ by a single amino acid. Tissue Antigens. 1999 Feb;53(2):111-21. [Content Brief]
- [2]. Herman J, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83. [Content Brief]
