1956337-58-8
Chemical Structure
IQM-266
- CAS No.: 1956337-58-8
- Formula:C25H19NO4
- Molecular Weight:397.42
IUPAC Name: 3-(2-(3-phenoxyphenyl)acetamido)-2-naphthoic acid
InChIKey: IQCQHKPTTDSXSZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C=CC=C2)=C2C=C1C(O)=O)CC3=CC(OC4=CC=CC=C4)=CC=C3
Biological Activity: IQM-266 is a Downstream Regulatory Element Antagonist Modulator (DREAM) ligand with a KD of 4.63 μM. IQM-266 inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. IQM-266 also modulates A-type outward potassium currents (IA) from rat dorsal root ganglia (DRG) neurons. IQM-266 can be used for neurological disease research, such as Alzheimer’s disease and Huntington's disease (HD)[1].
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IQM-266 | 99.42% | IQM-266 is a Downstream Regulatory Element Antagonist Modulator (DREAM) ligand with a KD of 4.63 μM. IQM-266 inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. IQM-266 also modulates A-type outward potassium currents (IA) from rat dorsal root ganglia (DRG) neurons. IQM-266 can be used for neurological disease research, such as Alzheimer’s disease and Huntington's disease (HD). | ||||||||||||||||||||
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Keywords
