1983984-01-5
Chemical Structure
Avotaciclib trihydrochloride
Synonym(s): BEY1107 trihydrochloride
- CAS No.: 1983984-01-5
- Formula:C13H14Cl3N7O
- Molecular Weight:390.66
IUPAC Name: 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol trihydrochloride
InChIKey: YUNYDIDVURXULR-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=NC(N)=NC=C2)N=C1C3=NC(N)=NC=C3.[H]Cl.[H]Cl.[H]Cl
Biological Activity: Avotaciclib (BEY1107) trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib trihydrochloride can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib trihydrochloride can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Avotaciclib trihydrochloride | 99.60% | Avotaciclib (BEY1107) trihydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib trihydrochloride can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib trihydrochloride can be used in the research of cancer such as pancreatic cancer and lung cancer. | ||||||||||||||||||||
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- [1]. Seufferlein T, et, al. Phase I Trials in Pancreatic Cancer. Translational Pancreatic Cancer Research pp 219-232.
- [2]. Zhang L, et al. Suppression of cyclin-dependent kinase 1 synergizes with checkpoint kinase 2 inhibitor to promote death of non-small cell lung cancer cells with radiotherapeutic resistance. Journal of Radiation Research and Applied Sciences, 2024, 17(2): 100900.
Keywords
