202646-03-5
202646-03-5
Chemical Structure
AHN 1-055 hydrochloride
Synonym(s): 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride
- CAS No.: 202646-03-5
- Formula:C21H24ClF2NO
- Molecular Weight:379.87
IUPAC Name: (1R,3r,5S)-3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride
InChIKey: YOORVSGDAHWVMC-BWSPSPBFSA-N
SMILES: CN1[C@@H]2C[C@@H](OC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C[C@H]1CC2.Cl
Biological Activity: AHN 1-055 hydrochloride is a dopamine uptake inhibitor that can cross the blood-brain barrier, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT)[1].
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AHN 1-055 hydrochloride | 99.96% | AHN 1-055 hydrochloride is a dopamine uptake inhibitor that can cross the blood-brain barrier, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT). | ||||||||||||||||||||
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AHN 1-055 hydrochloride (Standard) | ≥98% | AHN 1-055 (hydrochloride) (Standard) is the analytical standard of AHN 1-055 (hydrochloride) (HY-101315). This product is intended for research and analytical applications. AHN 1-055 hydrochloride is a dopamine uptake inhibitor, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT). | ||||||||||||||||||||
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References
- [1]. Sangeeta R, et, al. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis. Biopharm Drug Dispos. 2006 Jul; 27(5): 229-40. [Content Brief]
