2041789-14-2
2041789-14-2
Chemical Structure
HZ-A-005
- CAS No.: 2041789-14-2
- Formula:C25H23ClN6O2
- Molecular Weight:474.94
IUPAC Name: (S)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-chloroprop-2-en-1-one
InChIKey: ANUFNSMCYNDJKN-SFHVURJKSA-N
SMILES: C=C(C(N1CCC[C@@H](C1)N2N=C(C3=C(N=CN=C32)N)C4=CC=C(C=C4)OC5=CC=CC=C5)=O)Cl
Biological Activity: HZ-A-005 is a potent, selective, and covalent Bruton’s tyrosine kinase (BTK) inhibitor. HZ-A-005 markedly decreases tumor growth in xenograft mouse models[1].
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HZ-A-005 | HZ-A-005 is a potent, selective, and covalent Bruton’s tyrosine kinase (BTK) inhibitor. HZ-A-005 markedly decreases tumor growth in xenograft mouse models. | |||||||||||||||||||||
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References
Keywords
