204981-48-6

CP-195543 Chemical Structure
204981-48-6

Chemical Structure

CP-195543

  • CAS No.: 204981-48-6
  • Formula:C24H19F3O4
  • Molecular Weight:428.40

IUPAC Name: 2-((3S,4R)-3-benzyl-4-hydroxychroman-7-yl)-4-(trifluoromethyl)benzoic acid

InChIKey: NZQDWKCNBOELAI-KSFYIVLOSA-N

SMILES: O=C(O)C1=CC=C(C(F)(F)F)C=C1C2=CC=C3[C@H](O)[C@@H](CC4=CC=CC=C4)COC3=C2

Biological Activity: CP-195543 is a potent, selective and orally active leukotriene B4 (LTB4) receptor antagonist with IC50s of 6.8, 37.0 nM for human neutrophils and murine spleen membranes, respectively. CP-195543 blocks CD11b up-regulation. CP-195543 inhibits LTB4-mediated neutrophil infiltration[1].

Cat. No. Product Name Purity Description Pricing
HY-112742 		CP-195543 98.86% CP-195543 is a potent, selective and orally active leukotriene B4 (LTB4) receptor antagonist with IC50s of 6.8, 37.0 nM for human neutrophils and murine spleen membranes, respectively. CP-195543 blocks CD11b up-regulation. CP-195543 inhibits LTB4-mediated neutrophil infiltration.
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