2084913-49-3
Chemical Structure
H-L-Lys(4-N3-Z)-OH hydrochloride
- CAS No.: 2084913-49-3
- Formula:C14H20ClN5O4
- Molecular Weight:357.79
IUPAC Name: (R)-7-methoxy-8-((triisopropylsilyl)oxy)-10-((2-(trimethylsilyl)ethoxy)methyl)-1,11a-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-2,5,11(3H,10H)-trione
InChIKey: AQUASNYNCOKBBC-YDALLXLXSA-N
SMILES: OC([C@@H](N)CCCCNC(OCC1=CC=C(C=C1)N=[N+]=[N-])=O)=O.Cl
Biological Activity: H-L-Lys (4-N3-Z)-OH hydrochloride is an unnatural lysine analog and a substrate of the PABKRS mutant PylRS. H-L-Lys (4-N3-Z)-OH hydrochloride enables site-specific genetic integration into proteins via amber stop codon suppression; it undergoes Staudinger reduction with phosphine compounds, followed by a self-elimination reaction to release native lysine. H-L-Lys (4-N3-Z)-OH hydrochloride serves as a genetically encoded element for the temporal chemical control of protein SUMOylation and nuclear translocation in living mammalian cells, and also acts as a bioorthogonal reaction handle for bioconjugation reactions[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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H-L-Lys(4-N3-Z)-OH hydrochloride | 99.69% | H-L-Lys (4-N3-Z)-OH hydrochloride is an unnatural lysine analog and a substrate of the PABKRS mutant PylRS. H-L-Lys (4-N3-Z)-OH hydrochloride enables site-specific genetic integration into proteins via amber stop codon suppression; it undergoes Staudinger reduction with phosphine compounds, followed by a self-elimination reaction to release native lysine. H-L-Lys (4-N3-Z)-OH hydrochloride serves as a genetically encoded element for the temporal chemical control of protein SUMOylation and nuclear translocation in living mammalian cells, and also acts as a bioorthogonal reaction handle for bioconjugation reactions. | ||||||||||||||||||||
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