2084913-49-3
Chemical Structure
H-L-Lys(4-N3-Z)-OH hydrochloride
- CAS No.: 2084913-49-3
- Formula:C14H20ClN5O4
- Molecular Weight:357.79
IUPAC Name: N6-(((4-azidobenzyl)oxy)carbonyl)-L-lysine hydrochloride
InChIKey: AQUASNYNCOKBBC-YDALLXLXSA-N
SMILES: OC([C@@H](N)CCCCNC(OCC1=CC=C(C=C1)N=[N+]=[N-])=O)=O.Cl
Biological Activity: H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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H-L-Lys(4-N3-Z)-OH hydrochloride | 99.69% | H-L-Lys(4-N3-Z)-OH hydrochloride is a click chemistry reagent containing an azide group. H-L-Lys(4-N3-Z)-OH hydrochloride contains a lysine-modified azide moiety and as a bioorthogonal ligation handle. H-L-Lys(4-N3-Z)-OH hydrochloride is an infrared probe and a photo-affinity reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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- [1]. Ge Y, et, al. A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells. Chem Sci. 2016 Dec 1;7(12):7055-7060. [Content Brief]
- [2]. Wesalo JS, et, al. Phosphine-Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation. Chembiochem. 2020 Jan 15;21(1-2):141-148. [Content Brief]
Keywords
