2093421-02-2
2093421-02-2
Chemical Structure
QM385
- CAS No.: 2093421-02-2
- Formula:C17H18F3N7O2
- Molecular Weight:409.37
IUPAC Name: 2-(5-methyl-4-(4-(2,2,2-trifluoroethyl)piperazine-1-carbonyl)-1H-pyrazol-1-yl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one
InChIKey: GPMQVMCLRRPIIE-UHFFFAOYSA-N
SMILES: O=C1NC(N2N=CC(C(N3CCN(CC(F)(F)F)CC3)=O)=C2C)=NN4C1=CC=C4
Biological Activity: QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
QM385 | 99.48% | QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
