2135749-60-7
2135749-60-7
Chemical Structure
DN401
Synonym(s): Panvotinib-401; Pan-401
- CAS No.: 2135749-60-7
- Formula:C13H9BrClN5O2
- Molecular Weight:382.60
IUPAC Name: 1-((6-bromobenzo[d][1,3]dioxol-5-yl)methyl)-4-chloro-1H-pyrazolo[3,4-d]pyrimidin-6-amine
InChIKey: BIABSXPPEYWVER-UHFFFAOYSA-N
SMILES: NC1=NC(Cl)=C2C(N(N=C2)CC3=C(C=C4OCOC4=C3)Br)=N1
Biological Activity: DN401 is a potent TRAP1 inhibitor with an IC50 of 79 nM. DN401 shows a weak inhibition of Hsp90 (IC50 of 698 nM). DN401 inactivates mitochondrial TRAP1 and has potent anticancer activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DN401 | 98.64% | DN401 is a potent TRAP1 inhibitor with an IC50 of 79 nM. DN401 shows a weak inhibition of Hsp90 (IC50 of 698 nM). DN401 inactivates mitochondrial TRAP1 and has potent anticancer activities. | ||||||||||||||||||||
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