2140317-01-5
Chemical Structure
Regorafénib N-oxyde (M2)-13C,d3
- CAS No.: 2140317-01-5
- Formula:C2013CH12D3ClF4N4O4
- Molecular Weight:502.83
IUPAC Name: 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-((methyl-13C-d3)carbamoyl)pyridine 1-oxide
InChIKey: NUCXNEKIESREQY-KQORAOOSSA-N
SMILES: O=C(C1=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=CC=[N+]1[O-])N[13C]([2H])([2H])[2H]
Biological Activity: Regorafénib N-oxyde (M2)-13C,d3 is the 13C- and deuterium labeled Regorafénib N-oxyde (M2). Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
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Regorafénib N-oxyde (M2)-13C,d3 | Regorafénib N-oxyde (M2)-13C,d3 is the 13C- and deuterium labeled Regorafénib N-oxyde (M2). Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. | |||||||||||||||||||||
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Regorafénib N-oxyde (M2) (Standard) | ≥98% | Quinocetone (Standard) is the analytical standard of Quinocetone. This product is intended for research and analytical applications. Quinocetone is a potent synthetic antimicrobial agent that is used for improving the feed efficiency and controlling dysentery in food-producing animals. |
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Regorafénib N-oxyde-d3(M2) | Regorafénib N-oxyde-d3(M2) is the deuterium labeled Regorafénib N-oxyde M2. Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. | |||||||||||||||||||||
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Regorafénib N-oxyde (M2) | 98.15% | Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. | ||||||||||||||||||||
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