2213468-64-3
2213468-64-3
Chemical Structure
IIIM-290
- CAS No.: 2213468-64-3
- Formula:C23H21Cl2NO5
- Molecular Weight:462.32
IUPAC Name: 2-((E)-2,6-dichlorostyryl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one
InChIKey: NFTJDXGFOUFNKG-UGBNQVSOSA-N
SMILES: OC1=C2C(OC(/C=C/C3=C(Cl)C=CC=C3Cl)=CC2=O)=C([C@]4([H])[C@H](O)CN(C)CC4)C(O)=C1
Biological Activity: IIIM-290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2/A and CDK9/T1.
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IIIM-290 | IIIM-290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2/A and CDK9/T1. | |||||||||||||||||||||
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