2222465-34-9
Chemical Structure
CAP m7G(5')ppp(5')(2'OMeG)
- CAS No.: 2222465-34-9
- Formula:C22H31N10O18P3
- Molecular Weight:816.46
InChIKey: CUWKXCJRSKNYSN-QFPZEJIPSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COP(OP(OP(OC[C@H]4[C@H](O)[C@H](O)[C@@H](N5C6=C(C(N=C(N6)N)=O)[N+](C)=C5)O4)([O-])=O)(O)=O)(O)=O
Biological Activity: CAP m7G(5')ppp(5')(2'OMeG) is a dinucleotide cap analog that can be used as a monomeric raw material for nucleic acid synthesis. CAP m7G(5')ppp(5')(2'OMeG) can be synthesized from 2'-O-Methyl-GDP and 7-Methylguanosine under the catalysis of guanylate transferase, and can be used as an intermediate to synthesize Cap2 structure trinucleotide cap analogs. Research on the synthesis of CAP m7G(5')ppp(5')(2'OMeG) for mRNA cap analogs is underway[1].
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CAP m7G(5')ppp(5')(2'OMeG) | CAP m7G(5')ppp(5')(2'OMeG) is a dinucleotide cap analog that can be used as a monomeric raw material for nucleic acid synthesis. CAP m7G(5')ppp(5')(2'OMeG) can be synthesized from 2'-O-Methyl-GDP and 7-Methylguanosine under the catalysis of guanylate transferase, and can be used as an intermediate to synthesize Cap2 structure trinucleotide cap analogs. Research on the synthesis of CAP m7G(5')ppp(5')(2'OMeG) for mRNA cap analogs is underway. | |||||||||||||||||||||
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Keywords
