2235394-90-6

SHP389 Chemical Structure
2235394-90-6

Chemical Structure

SHP389

  • CAS No.: 2235394-90-6
  • Formula:C23H29ClN8O2
  • Molecular Weight:484.98

IUPAC Name: 6-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-3-(3-chloro-2-(cyclopropylamino)pyridin-4-yl)-5-methyl-2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

InChIKey: URUPFUYPXLMTMT-KPZWWZAWSA-N

SMILES: O=C1C2=C(C3=C(Cl)C(NC4CC4)=NC=C3)NN=C2N=C(N(CC5)CCC65[C@H](N)[C@H](C)OC6)N1C

Biological Activity: SHP389 is an allosteric SHP2 inhibitor, with an IC50 of 36 nM for both SHP2 and p-ERK[1].

Cat. No. Product Name Purity Description Pricing
HY-114453 		SHP389 98.03% SHP389 is an allosteric SHP2 inhibitor, with an IC50 of 36 nM for both SHP2 and p-ERK.
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