2241027-61-0
2241027-61-0
Chemical Structure
MEDS433
- CAS No.: 2241027-61-0
- Formula:C20H11F4N3O2
- Molecular Weight:401.31
InChIKey: JIIXZPWFDKPNKW-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC=CN2N=C1O)NC3=C(F)C(F)=C(C4=CC=CC=C4)C(F)=C3F
Biological Activity: MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MEDS433 | 99.51% | MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication. | ||||||||||||||||||||
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References
Keywords
