2310286-60-1
Chemical Structure
IDO1/2-IN-1 hydrochloride
- CAS No.: 2310286-60-1
- Formula:C16H19BrClFN8O4
- Molecular Weight:521.73
IUPAC Name: (E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(4-((2-hydroxyethoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide hydrochloride
InChIKey: OFKAFAFCZQUHPC-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1Br)/N=C(C2=NON=C2NCCN3N=NC(COCCO)=C3)/NO.[H]Cl
Biological Activity: IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active[1].
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IDO1/2-IN-1 hydrochloride | IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active. | |||||||||||||||||||||
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Keywords
