2365172-82-1
Chemical Structure
Desmorpholinyl navitoclax-NH-Me
Synonym(s): Desmorpholinyl ABT-263-NH-Me
- CAS No.: 2365172-82-1
- Formula:C44H51ClF3N5O5S3
- Molecular Weight:918.55
IUPAC Name: (R)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-(methylamino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide
InChIKey: CNTHZPROCQHGOX-PGUFJCEWSA-N
SMILES: O=C(C1=CC=C(N2CCN(CC3=C(C4=CC=C(Cl)C=C4)CCC(C)(C)C3)CC2)C=C1)NS(C5=CC(S(=O)(C(F)(F)F)=O)=C(N[C@@H](CSC6=CC=CC=C6)CCNC)C=C5)(=O)=O
Biological Activity: Desmorpholinyl navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is an N-methylamino-substituted derivative of Navitoclax (HY-10087) and a BCL-XL-targeting PROTAC precursor. Desmorpholinyl navitoclax-NH-Me is used for the synthesis of BCL-XL-targeting PROTACs and related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Desmorpholinyl navitoclax-NH-Me | 98.64% | Desmorpholinyl navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is an N-methylamino-substituted derivative of Navitoclax (HY-10087) and a BCL-XL-targeting PROTAC precursor. Desmorpholinyl navitoclax-NH-Me is used for the synthesis of BCL-XL-targeting PROTACs and related research. | ||||||||||||||||||||
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