2374856-75-2

Evixapodlin Chemical Structure
2374856-75-2

Chemical Structure

Evixapodlin

Synonym(s): GS-4224; PD-1/PD-L1-IN 7

  • CAS 番号: 2374856-75-2
  • Formula:C34H36Cl2N8O4
  • Molecular Weight:691.61

IUPAC Name: (5S,5'S)-5,5'-(((((2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one)

InChIKey: OIIOPWHTJZYKIL-PMACEKPBSA-N

SMILES: ClC1=C(C(C=CC=C2C(C=N3)=NC(OC)=C3CNC[C@H](CC4)NC4=O)=C2Cl)C=CC=C1C(C=N5)=NC(OC)=C5CNC[C@H](CC6)NC6=O

Biological Activity: Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions[1].

製品番号 製品名 純度 製品説明 Pricing
HY-138407
Evixapodlin 98.14% Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References