2382959-65-9
2382959-65-9
Chemical Structure
Topoisomerase II inhibitor 18
- CAS No.: 2382959-65-9
- Formula:C20H21N3OS
- Molecular Weight:351.47
InChIKey: SQUOYGKGBLGUGQ-UHFFFAOYSA-N
SMILES: O=C(NCCC)CCSC1=NC2=CC=CC=C2N=C1C3=CC=CC=C3
Biological Activity: Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC50 of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer[1].
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Topoisomerase II inhibitor 18 | Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC50 of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer. | |||||||||||||||||||||
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