2412144-74-0
2412144-74-0
Chemical Structure
Aurora A inhibitor 2
- CAS 番号: 2412144-74-0
- Formula:C24H26N6O3
- Molecular Weight:446.50
IUPAC Name: N-(6-(3-(2-morpholinoethyl)-4-oxo-3,4-dihydroquinazolin-6-yl)-1H-benzo[d]imidazol-2-yl)propionamide
InChIKey: WKBADCPZJIWSRC-UHFFFAOYSA-N
SMILES: CCC(NC1=NC2=CC=C(C3=CC4=C(N=CN(CCN5CCOCC5)C4=O)C=C3)C=C2N1)=O
Biological Activity: Aurora A inhibitor 2 (Compound 16h) is a potent Aurora A kinase inhibitor with an IC50 of 21.94 nM. Aurora A inhibitor 2 induces caspase-dependent apoptosis in MDA-MB-231 cells[1].
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Aurora A inhibitor 2 | Aurora A inhibitor 2 (Compound 16h) is a potent Aurora A kinase inhibitor with an IC50 of 21.94 nM. Aurora A inhibitor 2 induces caspase-dependent apoptosis in MDA-MB-231 cells. | |||||||||||||||||||||
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