2416910-94-4
2416910-94-4
Chemical Structure
AChE/BChE-IN-6
- CAS No.: 2416910-94-4
- Formula:C23H30N2O2
- Molecular Weight:366.50
IUPAC Name: (1-benzylpiperidin-4-yl)methyl (4-isopropylphenyl)carbamate
InChIKey: WSZHWBCEOHXGOF-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)NC(OCC2CCN(CC2)CC3=CC=CC=C3)=O)C
Biological Activity: AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 µM, 2.248 µM and > 100 µM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB). AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research[1].
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AChE/BChE-IN-6 | AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 µM, 2.248 µM and > 100 µM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB). AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research. | |||||||||||||||||||||
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References
Keywords
