2428389-66-4
Chemical Structure
α-Glycosidase-IN-1
- CAS No.: 2428389-66-4
- Formula:C21H19N9O6S2
- Molecular Weight:557.56
IUPAC Name: 4,4'-((6-((3-nitrophenyl)amino)-1,3,5-triazine-2,4-diyl)bis(azanediyl))dibenzenesulfonamide
InChIKey: UYTXZVYAKOGUEL-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC(NC2=NC(NC3=CC=C(S(=O)(N)=O)C=C3)=NC(NC4=CC=C(S(=O)(N)=O)C=C4)=N2)=CC=C1)[O-]
Biological Activity: α-Glycosidase-IN-1 (compound MZ7) is a potent α-GLY (α-Glycosidase) inhibitor, with an IC50 of 44.72 nM and a KI of 41.74 nM. α-Glycosidase-IN-1 also shows inhibition profile against human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), and acetylcholinesterase (AChE), with IC50 values of 104.87, 100.04, and 654.87 nM, respectively. α-Glycosidase-IN-1 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy[1].
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α-Glycosidase-IN-1 | α-Glycosidase-IN-1 (compound MZ7) is a potent α-GLY (α-Glycosidase) inhibitor, with an IC50 of 44.72 nM and a KI of 41.74 nM. α-Glycosidase-IN-1 also shows inhibition profile against human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), and acetylcholinesterase (AChE), with IC50 values of 104.87, 100.04, and 654.87 nM, respectively. α-Glycosidase-IN-1 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy. | |||||||||||||||||||||
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Keywords
