2447597-39-7
2447597-39-7
Chemical Structure
VEGFR-2-IN-28
- CAS No.: 2447597-39-7
- Formula:C26H17N7O7
- Molecular Weight:539.46
IUPAC Name: (E)-2-(2,4-dinitrophenyl)-5-methyl-4-((3-(3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2,4-dihydro-3H-pyrazol-3-one
InChIKey: PHOMMXJDCXTWKV-LPYMAVHISA-N
SMILES: O=C(N(C1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)N=C/2C)C2=C\C3=CN(C4=CC=CC=C4)N=C3C5=CC=CC([N+]([O-])=O)=C5
Biological Activity: VEGFR-2-IN-28 (compound 12c) is a potent VEGFR-2 inhibitor with IC50 value of 0.83 µM. VEGFR-2-IN-28 induces apoptosis and has anticancer activity[1].
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VEGFR-2-IN-28 | VEGFR-2-IN-28 (compound 12c) is a potent VEGFR-2 inhibitor with IC50 value of 0.83 µM. VEGFR-2-IN-28 induces apoptosis and has anticancer activity. | |||||||||||||||||||||
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