2459892-41-0
Chemical Structure
Antiproliferative agent-5
- CAS No.: 2459892-41-0
- Formula:C28H21BrN8OS
- Molecular Weight:597.49
IUPAC Name: (E)-1-(4-((2-(((1H-benzo[d]imidazol-2-yl)methyl)thio)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amino)phenyl)-3-(6-bromopyridin-2-yl)prop-2-en-1-one
InChIKey: OVYBJFROGFLPKU-BUHFOSPRSA-N
SMILES: O=C(C1=CC=C(NC2=CC(C)=NC3=NC(SCC4=NC5=CC=CC=C5N4)=NN23)C=C1)/C=C/C6=NC(Br)=CC=C6
Biological Activity: Antiproliferative agent-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative agent-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative agent-5 can be used for researching anticancer[1].
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Antiproliferative agent-5 | Antiproliferative agent-5 (compound 4o) can significantly and irreversibly inhibit proliferation of gastric cancer cells. Antiproliferative agent-5 causes the G2/M phase arrest, and induces ROS accumulation and activation of autophagy. Antiproliferative agent-5 can be used for researching anticancer. | |||||||||||||||||||||
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Keywords