2488951-93-3
2488951-93-3
Chemical Structure
PKCζ-IN-2
- CAS No.: 2488951-93-3
- Formula:C21H23FN4
- Molecular Weight:350.43
InChIKey: NTJHXOPWIGBYGG-KRWDZBQOSA-N
SMILES: NC1=CC(F)=C(C2=CC3=CN=CC=C3C(N[C@H]4CCCCNC4)=C2)C=C1
Biological Activity: PKCζ-IN-2 is an orally active, selective PKCζ inhibitor with an IC50 of 0.1 nM. As an anti-inflammatory agent, PKCζ-IN-2 reduces joint swelling and ameliorates disease progression in a mouse collagen-induced arthritis model. PKCζ-IN-2 can be used for the research of rheumatoid arthritis[1].
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PKCζ-IN-2 | PKCζ-IN-2 is an orally active, selective PKCζ inhibitor with an IC50 of 0.1 nM. As an anti-inflammatory agent, PKCζ-IN-2 reduces joint swelling and ameliorates disease progression in a mouse collagen-induced arthritis model. PKCζ-IN-2 can be used for the research of rheumatoid arthritis. | |||||||||||||||||||||
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