2498658-20-9
2498658-20-9
Chemical Structure
CDK2-IN-61
- CAS No.: 2498658-20-9
- Formula:C21H25N5O4S
- Molecular Weight:443.52
InChIKey: AKQOBHZKBDHWQI-HUUCEWRRSA-N
SMILES: O=C1C2(CC2)C3=CN=C(NC4=CC=C(C=C4)S(NC)(=O)=O)N=C3N1[C@H]5C[C@@H](CCC5)O
Biological Activity: CDK2-IN-61 is a highly selective CDK2 inhibitor with a human IC50 of 0.25 nM. CDK2-IN-61 can be used in cancer-related research[1].
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CDK2-IN-61 | CDK2-IN-61 is a highly selective CDK2 inhibitor with a human IC50 of 0.25 nM. CDK2-IN-61 can be used in cancer-related research. | |||||||||||||||||||||
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CDK2-IN-46 | CDK2-IN-46 (compound 5g) is a selective CDK2 inhibitor with an IC50 of 0.3 nM. CDK2-IN-46 has a selectivity of >200-fold for CDK1, CDK7, CDK9, CDK4, and CDK6. CDK2-IN-46 shows improves rat and cyno pharmacokinetic profiles. | |||||||||||||||||||||
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References
Keywords
