2624181-61-7
2624181-61-7
Chemical Structure
Pomalidomide 4'-PEG5-azide
- CAS No.: 2624181-61-7
- Formula:C25H34N6O9
- Molecular Weight:562.57
IUPAC Name: 4-((17-azido-3,6,9,12,15-pentaoxaheptadecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChIKey: GQNYHWLPMGECRM-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
Biological Activity: Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC[1].
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Pomalidomide 4'-PEG5-azide | Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC. | |||||||||||||||||||||
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References
Keywords
