2640287-77-8
2640287-77-8
Chemical Structure
PRMT5-IN-48
- CAS No.: 2640287-77-8
- Formula:C30H37N5O3
- Molecular Weight:515.65
InChIKey: PEYPSWDNEDTZFS-XMMPIXPASA-N
SMILES: O=C1C2=CC(NC3CC4(C3)CN(C4)C(C)=O)=NC=C2C5(CN1C[C@@H](CN6CCC(C=CC=C7)=C7C6)O)CC5
Biological Activity: PRMT5-IN-48 (compound D3) is an orally effective PRMT5 inhibitor (IC50=20.7 nM) with anticancer activity. PRMT5-IN-48 can inhibit the growth of various cancer cells, induce apoptosis (apoptosis), and arrest the cell cycle at the G0/G1 phase. PRMT5-IN-48 can be used for non-Hodgkin lymphoma (NHL) research[1].
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PRMT5-IN-48 | PRMT5-IN-48 (compound D3) is an orally effective PRMT5 inhibitor (IC50=20.7 nM) with anticancer activity. PRMT5-IN-48 can inhibit the growth of various cancer cells, induce apoptosis (apoptosis), and arrest the cell cycle at the G0/G1 phase. PRMT5-IN-48 can be used for non-Hodgkin lymphoma (NHL) research. | |||||||||||||||||||||
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References
Keywords
