267665-69-0
267665-69-0
Chemical Structure
2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine
- CAS No.: 267665-69-0
- Formula:C30H30N2O5S
- Molecular Weight:530.63
IUPAC Name: 1-((2R,3S,4S,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: QAPVNIXRVZNZPK-HVQBEUSNSA-N
SMILES: O=C(C=C1)NC(N1[C@@H]2S[C@H](COCC3=CC=CC=C3)[C@@H](OCC4=CC=CC=C4)[C@@H]2OCC5=CC=CC=C5)=O
Biological Activity: 2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine | 2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
