270919-17-0
Chemical Structure
Tet1 peptide
- CAS No.: 270919-17-0
- Formula:C73H114N20O17
- Molecular Weight:1543.81
InChIKey: LOTKNMLPGOYDLQ-LSCCZYFVSA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CNC=N4)N
Biological Activity: Tet1 peptide is a peptide that specifically binds to neurons. Tet1 peptide binds to GT1B ganglioside and trisialoganglioside clostridial toxin receptor on the surface of neuronal cells, and can be used in peptide conjugation and drug delivery research[1][2].
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Tet1 peptide | Tet1 peptide is a peptide that specifically binds to neurons. Tet1 peptide binds to GT1B ganglioside and trisialoganglioside clostridial toxin receptor on the surface of neuronal cells, and can be used in peptide conjugation and drug delivery research. | |||||||||||||||||||||
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- [1]. Wang P, et al. Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease. J Control Release. 2018;279:220-233. [Content Brief]
- [2]. Zhang Y, et al. Targeted delivery of Tet1 peptide functionalized polymersomes to the rat cochlear nerve. Int J Nanomedicine. 2012;7:1015-1022. [Content Brief]
Keywords
