2758265-36-8
Chemical Structure
Hancockiamide C
- CAS No.: 2758265-36-8
- Formula:C31H32N2O5
- Molecular Weight:512.61
IUPAC Name: (E)-1-((2S,5S)-4-acetyl-5-benzyl-2-((7-methoxybenzo[d][1,3]dioxol-5-yl)methyl)piperazin-1-yl)-3-phenylprop-2-en-1-one
InChIKey: RVLALFABWNVGIS-HKRYAFHYSA-N
SMILES: C([C@@H]1N(C(/C=C/C2=CC=CC=C2)=O)C[C@H](CC3=CC=CC=C3)N(C(C)=O)C1)C=4C=C5C(=C(OC)C4)OCO5
Biological Activity: Hancockiamide C is a phenylacetic piperazine natural products found in Aspergillus hancockii. Hancockiamide C is synthesized via the hkm biosynthetic gene cluster, involving NRPS Hkm11 and the acetyltransferase Hkm3. Hancockiamide C inhibits seed germination of Arabidopsis thaliana (MIC = 6.3 μg/mL), but shows no activity against Eragrostis tef seeds[1].
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Hancockiamide C | Hancockiamide C is a phenylacetic piperazine natural products found in Aspergillus hancockii. Hancockiamide C is synthesized via the hkm biosynthetic gene cluster, involving NRPS Hkm11 and the acetyltransferase Hkm3. Hancockiamide C inhibits seed germination of Arabidopsis thaliana (MIC = 6.3 μg/mL), but shows no activity against Eragrostis tef seeds. | |||||||||||||||||||||
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