2764748-92-5
2764748-92-5
Chemical Structure
Carboxylesterase-IN-3
- CAS No.: 2764748-92-5
- Formula:C11H6Cl2N4OS
- Molecular Weight:313.16
IUPAC Name: 6-((3,4-dichlorophenyl)thio)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one
InChIKey: DYBIDXYUMDMCON-UHFFFAOYSA-N
SMILES: O=C1NN=C2C=CC(SC3=CC=C(Cl)C(Cl)=C3)=NN21
Biological Activity: Carboxylesterase-IN-3 (compound 4y) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-3 has the potential for the research of cancer disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Carboxylesterase-IN-3 | 98.27% | Carboxylesterase-IN-3 (compound 4y) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-3 has the potential for the research of cancer disease. | ||||||||||||||||||||
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