Carboxylesterase-IN-3
Based on 1 Customer Validation
Carboxylesterase-IN-3 (compound 4y) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-3 has the potential for the research of cancer disease.
For research use only. We do not sell to patients.
- Purity: 98.27%
- CAS No.: 2764748-92-5
- Formula: C11H6Cl2N4OS
- Molecular Weight:313.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Stem Cell Signaling Compound Library
HY-L017
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Wnt/Hedgehog/Notch Compound Library
HY-L020
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Cytoskeleton Compound Library
HY-L060
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Neuroprotective Compound Library
HY-L070
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Anti-Breast Cancer Compound Library
HY-L074
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Protein-protein Interaction Inhibitor Library
HY-L109
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Extracellular Vesicles (EVs) Compound Library
HY-L168
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Chemical Information
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CAS No. 2764748-92-5
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Appearance Solid
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Molecular Weight 313.16
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Formula C11H6Cl2N4OS
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Color Light yellow to yellow
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SMILES
O=C1NN=C2C=CC(SC3=CC=C(Cl)C(Cl)=C3)=NN21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (319.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1933 mL | 15.9663 mL | 31.9326 mL | 79.8314 mL |
| 5 mM | 0.6387 mL | 3.1933 mL | 6.3865 mL | 15.9663 mL | |
| 10 mM | 0.3193 mL | 1.5966 mL | 3.1933 mL | 7.9831 mL | |
| 15 mM | 0.2129 mL | 1.0644 mL | 2.1288 mL | 5.3221 mL | |
| 20 mM | 0.1597 mL | 0.7983 mL | 1.5966 mL | 3.9916 mL | |
| 25 mM | 0.1277 mL | 0.6387 mL | 1.2773 mL | 3.1933 mL | |
| 30 mM | 0.1064 mL | 0.5322 mL | 1.0644 mL | 2.6610 mL | |
| 40 mM | 0.0798 mL | 0.3992 mL | 0.7983 mL | 1.9958 mL | |
| 50 mM | 0.0639 mL | 0.3193 mL | 0.6387 mL | 1.5966 mL | |
| 60 mM | 0.0532 mL | 0.2661 mL | 0.5322 mL | 1.3305 mL | |
| 80 mM | 0.0399 mL | 0.1996 mL | 0.3992 mL | 0.9979 mL | |
| 100 mM | 0.0319 mL | 0.1597 mL | 0.3193 mL | 0.7983 mL |
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