2764787-76-8
2764787-76-8
Chemical Structure
HIV-1 inhibitor-17
- CAS No.: 2764787-76-8
- Formula:C32H32N4O5S
- Molecular Weight:584.69
IUPAC Name: (S)-3-((5-aminoindolin-1-yl)sulfonyl)-N-(1-((4-methoxyphenyl)(methyl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide
InChIKey: VCNYRIZWJWIDIN-LJAQVGFWSA-N
SMILES: O=C(N[C@@H](CC1=CC=CC=C1)C(N(C2=CC=C(OC)C=C2)C)=O)C3=CC=CC(S(=O)(N4CCC5=C4C=CC(N)=C5)=O)=C3
Biological Activity: HIV-1 inhibitor-18 (compound V-25i) is a potent HIV-1 capsid inhibitor with an EC50 value of 2.57 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >8.55)[1].
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HIV-1 inhibitor-17 | HIV-1 inhibitor-18 (compound V-25i) is a potent HIV-1 capsid inhibitor with an EC50 value of 2.57 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >8.55). | |||||||||||||||||||||
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References
Keywords
